Late J Jayalalitha began her acting career in 1964 at the young age of 15. In Tollywood, She made her debut as lead actress in an Akkineni Nageshwara Rao starrer Manushulu Mamathalu in 1965. Later she acted in many hit movies in Telugu cinema.What is interesting is that her last Telugu release was also an ANR starrer. She played as his heroine in film called Nayakudu Vinayakudu that was released in 1980.  Jayalalitha had done seven films with Akkineni Nageswara Rao.

She also appeared in bikini in a Telugu movie.

Her list of Telugu movies..

• Manushulu Mamathalu (1965)
• Kathanayakuni Katha (1965)
• Aame Yevaru (1966)
• Astiparulu (1966)
• Gudachari 116 (1966)
• Navaratri (1966)
• Gopaludu Bhoopaludu (1967)
• Chikkadu Dorakadu (1967)
• Dhaname Prapancha Leela (1967)
• Nuvve (1967)
• Brahmachari (1967)
• Sukadukhalu (1967)
• Adrustavanthulu (1968)
• Tikka Shankaraiah (1968)
• Coiambatore Khaidi (1968)
• Niluvu Dopidi (1968)
• Baghdad Gaja Donga (1968)
• Dopidi Dongalu (1968)
• Poola Pilla (1968)
• Pellante Bhayam (1968)
• Sri Rama Katha (1968)
• Adarsha Kutumbam (1969)
• Kathanayakudu (1969)
• Kadaladu Vadaladu (1969)
• Panchakalyani Dongala Rani
• Gandikota Rahasyam (1970)
• Koteeshwarudu (1970)
• Ali Baba 40 Dongalu (1970)
• Shri Krishna Vijayam (1970)
• Meme Monagallamu (1971)
• Shri Krishna Satya (1971)
• Bharya Biddalu (1972)
• Doctor Babu (1973)
• Devudu Chesina Manushulu (1973)
• Nayakudu vinayakudu (1980)